The Insider.com

"I look like the Predator with hepatitis," was just one of the descriptions Conan O'Brien used to describe his new dreadlocks and orange hue on Thursday night.

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O'Brien's late night co-host Andy Richter also had some jokes regarding his new look calling him the "starting center for the Oompa Loompa basketball team" and referring to him as Bo Derek from 10.

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The host, 49, also said of his look, "By the way, my audition for the Jersey Shore went quite well. I really aced that thing."

This new, oranger O'Brien was all in good fun and more importantly, for a good cause. It is to benefit autism research in support of A Night of Too Many Stars.

The jokes didn't stop with the monologue. Check out Mentalist star Simon Baker's reaction to the dreadlocks.